Vitamin A circulates in the blood as retinol bound to retinol-binding protein. Levels reflect both dietary intake and the liver's ability to release stored vitamin A. Deficiency commonly results from malabsorption disorders, while excess can occur with excessive supplementation or treatment with certain retinoid medications.
This test is used to investigate visual or skin changes suggestive of vitamin A deficiency, evaluate patients with malabsorption, monitor vitamin A status in patients on prescribed retinoids, and assess possible toxicity. Sample type is serum or plasma.
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