VDRL (Venereal Disease Research Laboratory) is a non-treponemal antibody test for syphilis, similar to RPR. When the initial screen is positive, the reflex titer measures antibody quantity, which is essential for assessing disease activity and monitoring treatment response. Positive screens typically require confirmation with a treponemal-specific test.
This test is used for syphilis screening, evaluation of suspected syphilis, and monitoring of treatment response. Falling titers after treatment indicate effective therapy. Sample type is serum.