Tobramycin is an aminoglycoside antibiotic effective against many gram-negative bacteria but with significant kidney and ear toxicity risk. Trough levels — typically targeted below specified thresholds — help minimize toxicity, while peak levels may be measured to ensure adequate exposure.
This test is used in patients on tobramycin for serious gram-negative infections, particularly when prolonged therapy or higher doses are used. Sample type is serum or plasma, drawn just before the next scheduled dose.
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