Cascade testing follows current guidelines for evaluating thyroid function: TSH is measured first, with free T4, free T3, and/or antibody testing added automatically if the initial result is abnormal. This approach delivers a complete picture of thyroid function when needed while avoiding unnecessary cost for patients with normal thyroid function.
This profile is used in routine thyroid screening, evaluation of nonspecific symptoms suggestive of thyroid dysfunction, monitoring of patients with treated thyroid disease, and assessment in pregnancy or fertility care. The reflex design ensures abnormal initial results are promptly characterized. Sample type is serum.