Tapentadol (Nucynta) is an opioid analgesic with a unique dual mechanism — opioid receptor agonist and norepinephrine reuptake inhibitor. Standard opiate immunoassays do not detect tapentadol; LC-MS/MS testing identifies it with specificity.
This test is used in pain management to verify compliance with prescribed tapentadol, evaluate possible misuse, and provide medico-legal documentation. Sample type is urine.
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