When serum protein electrophoresis shows a possible monoclonal protein (M-protein), immunofixation (IFE) is performed automatically to identify which immunoglobulin class and light chain are involved. This reflex approach saves time and avoids a second blood draw.
This test is used to evaluate suspected multiple myeloma, monoclonal gammopathy of undetermined significance (MGUS), Waldenström macroglobulinemia, light chain amyloidosis, and other plasma cell or B-cell disorders. Sample type is serum.
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