PSA can be elevated in prostate cancer, but also in benign prostate enlargement, prostatitis, urinary tract infection, and after procedures involving the prostate. Because of this, PSA results are interpreted in context with age, prostate size, rate of change over time, and clinical findings.
This test is used to screen for prostate cancer in eligible men (discussions about benefits and risks of screening are encouraged), monitor patients with known prostate cancer for treatment response and recurrence, and evaluate symptoms such as urinary changes. PSA velocity and density may add interpretive value in selected cases. Sample type is serum.
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