Progesterone rises sharply in the second half of the menstrual cycle following ovulation and remains elevated if pregnancy occurs. Its presence and pattern provide important information about reproductive function.
This test is used to confirm ovulation in women being evaluated for infertility, assess the viability of early pregnancy (particularly when ectopic or failing pregnancy is suspected), monitor progesterone supplementation during fertility treatment or early pregnancy, and help evaluate abnormal uterine bleeding. In some cases it is also used to investigate certain adrenal disorders. The timing of the blood draw within the menstrual cycle is critical for accurate interpretation. Sample type is serum.