Most of the body's phosphorus is stored in bones with calcium, but a small fraction circulates in the blood, where it plays critical roles in energy production, nerve signaling, and cell membrane structure. Phosphorus levels are tightly regulated by the kidneys and parathyroid hormone.
This test is ordered to evaluate kidney disease (where phosphorus often rises), parathyroid disorders, refeeding syndrome in malnourished patients, and unexplained bone pain or muscle weakness. It is typically interpreted alongside calcium and PTH for a complete picture of mineral metabolism. Sample type is serum.
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