Opioid antagonists block the effects of opioids. Naltrexone is prescribed long-term for opioid use disorder treatment, while naloxone is the rescue medication for opioid overdose. LC-MS/MS testing identifies these compounds and their metabolites, useful for monitoring compliance with antagonist therapy.
This test is used in addiction medicine to verify compliance with prescribed naltrexone therapy, document recent naloxone administration, and provide medico-legal documentation. Sample type is urine.
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