LC-MS/MS testing identifies specific opiates and metabolites — including morphine, codeine, hydrocodone, hydromorphone, oxycodone, oxymorphone, and 6-monoacetylmorphine — at very low concentrations. Compared to immunoassay screening, it provides definitive identification of specific substances, eliminates many cross-reactivity issues, and quantifies levels.
This test is used in pain management monitoring, addiction treatment, post-screening confirmation, and forensic settings. Detection windows vary by drug — most opiates are detectable in urine for 1-3 days after use. Sample type is urine, with strict collection protocols when chain of custody is required.
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