Magnesium is involved in hundreds of biochemical reactions, and abnormal levels can affect nearly every organ system. Low magnesium is common in malnutrition, alcohol use, gastrointestinal losses, and certain diuretic therapies, while high magnesium most often occurs in kidney failure or excessive supplementation.
This test is ordered to investigate muscle cramps, weakness, tremors, or unexplained arrhythmias; evaluate patients with suspected nutritional deficiencies, malabsorption, or chronic alcohol use; monitor patients on diuretics or medications affecting electrolytes; and assess critically ill or hospitalized patients. Magnesium is often interpreted alongside calcium and potassium, since deficiencies frequently coexist. Sample type is serum.