This combined panel includes serum protein electrophoresis (which detects abnormal protein bands), immunofixation (which identifies monoclonal proteins), and quantitative free kappa and lambda light chains with their ratio. Together, these tests provide the most sensitive and specific assessment of monoclonal gammopathies.
This panel is used in initial evaluation of suspected multiple myeloma, AL amyloidosis, MGUS, and related plasma cell disorders. It is also valuable for monitoring response to treatment and detecting recurrence. Sample type is serum.
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