Drug testing typically uses a two-step approach: initial screening by immunoassay (sensitive but with some cross-reactivity), followed by confirmation of positives using LC-MS/MS (highly specific). Reflex testing combines these steps automatically, ensuring rapid, accurate results without needing separate orders.
This testing strategy is used in pain management, addiction treatment, workplace drug testing, and forensic settings where definitive identification of specific substances is required. Sample type is urine, often under chain-of-custody protocols.