This combined test measures the precise amount of HCV RNA in the blood (viral load) and identifies which of the six major HCV genotypes is present. Together, these results confirm active infection, establish baseline viral burden, and inform treatment decisions, since some direct-acting antivirals are genotype-specific.
This test is used after a positive HCV antibody screen to confirm active infection, before initiating antiviral therapy to guide drug selection and treatment duration, and to establish a baseline for monitoring response. Sample type is serum or plasma.