Unlike antibody testing, which only confirms past exposure, stool antigen testing specifically identifies active infection. It is highly accurate, noninvasive, and useful both for initial diagnosis and for confirming successful treatment.
This test is used to diagnose suspected active H. pylori infection in patients with dyspepsia or peptic ulcer disease and to confirm cure several weeks after completing eradication therapy. Patients should be off proton pump inhibitors for at least two weeks before testing for the most accurate results. Sample type is a stool specimen.
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