Ferritin reflects the amount of iron stored in the body and is the most sensitive early marker of iron deficiency, often dropping before red blood cells are affected. Low ferritin almost always indicates iron deficiency, while elevated ferritin can indicate iron overload disorders such as hemochromatosis, chronic inflammation, liver disease, or certain cancers.
This test is commonly ordered to evaluate anemia, investigate fatigue, monitor patients with chronic kidney disease or those on iron supplementation, and screen for hereditary hemochromatosis. Because ferritin also rises with inflammation, results are best interpreted alongside other tests like CRP and iron studies. Sample type is serum.
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