EBV PCR detects and quantifies the virus directly, which is especially important in transplant recipients and other immunocompromised patients where reactivation can cause post-transplant lymphoproliferative disease (PTLD) or other EBV-associated complications. Quantitative measurement allows tracking of viral burden over time.
This test is used in post-transplant monitoring, evaluation of suspected PTLD, assessment of EBV-associated cancers (such as nasopharyngeal carcinoma or Burkitt lymphoma), and certain cases of chronic active EBV. Sample type is whole blood, plasma, or tissue.