Shiga toxin-producing E. coli (STEC), including the well-known E. coli O157:H7, cause foodborne illness characterized by bloody diarrhea and abdominal cramps. The toxin can lead to hemolytic uremic syndrome (HUS), a life-threatening complication particularly in young children and the elderly. Antibiotics are generally avoided in STEC infection because they may increase HUS risk.
This test is ordered when STEC infection is suspected — particularly in patients with bloody diarrhea, recent suspect food exposures (such as undercooked beef, unpasteurized dairy, or raw produce), and during outbreak investigations. Rapid identification supports clinical management and public health response. Sample type is a stool specimen.