Blood culture involves drawing blood into special bottles that promote growth of any microorganisms present, followed by identification and susceptibility testing of any organisms that grow. Multiple sets from different sites are typically collected to improve sensitivity and help distinguish true bloodstream infections from skin contamination.
This test is essential when sepsis is suspected, for evaluation of unexplained fever, in patients with possible endocarditis, and before starting antibiotics in seriously ill patients. Identifying the responsible organism and its antibiotic susceptibility profile is critical for choosing effective treatment. Sample type is blood collected in aerobic and anaerobic culture bottles.