VEB, PER, and GES are less common ESBL families than CTX-M, SHV, and TEM, but their detection is important because they convey similar resistance patterns. They are found in Pseudomonas, Acinetobacter, and certain Enterobacterales, particularly in nosocomial and travel-associated infections.
Detection of these genes in molecular susceptibility testing guides antibiotic selection — typically toward carbapenems or newer agents — in serious gram-negative infections. Sample type is typically a culture isolate or direct clinical specimen.
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