Standard CRP testing is useful for detecting significant inflammation, but hs-CRP measures much lower levels relevant to cardiovascular disease. Low-grade systemic inflammation contributes to atherosclerosis, and hs-CRP refines cardiovascular risk prediction, particularly in patients with intermediate risk profiles.
This test is typically ordered alongside lipid profiles in apparently healthy adults to refine cardiovascular risk assessment. Results are generally interpreted in three tiers: low (under 1 mg/L), average (1-3 mg/L), and high (over 3 mg/L). It is most useful when standard risk assessment is borderline and may influence preventive treatment decisions. Sample type is serum.