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blaMOX

blaMOX is a plasmid-mediated AmpC beta-lactamase that hydrolyzes cephalosporins including third-generation drugs. Like other AmpC enzymes, it is not inhibited by clavulanate or tazobactam, limiting use of beta-lactam/inhibitor combinations.

Detection of blaMOX in molecular testing identifies organisms requiring carbapenems or newer combinations for effective treatment. Sample type is typically a culture isolate or direct clinical specimen.

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