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blaFOX

blaFOX is a plasmid-mediated AmpC beta-lactamase that hydrolyzes cephalosporins, including third-generation drugs and cephamycins like cefoxitin. It resists common beta-lactamase inhibitors, limiting treatment options.

Detection of blaFOX in molecular testing identifies organisms requiring carbapenems or newer beta-lactam/inhibitor combinations for effective treatment. Sample type is typically a culture isolate or direct clinical specimen.

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