blaACT is a plasmid-mediated AmpC beta-lactamase that hydrolyzes cephalosporins, including third-generation drugs. Like other AmpC enzymes, it is not inhibited by clavulanate or tazobactam.
Detection of blaACT in molecular testing identifies organisms requiring carbapenems or newer beta-lactam/inhibitor combinations for effective treatment. Sample type is typically a culture isolate or direct clinical specimen.
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